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This document describes activities performed with support from the Office of Domestic and International Health Studies, Office of Health and Safety of the U. S. Department of Energy (DOE), and was performed at the Center for Epidemiologic Research at the Oak Ridge Institute for Science and Education (ORISE), which is managed by Oak Ridge Associated Universities under contract number DE-AC05-06OR23100. ORISE is a DOE institute focusing on scientific initiatives to research health risks from occupational hazards, assess environmental cleanup, respond to radiation medical emergencies, support national security and emergency preparedness, and educate the next generation of scientists. Additional support was provided by Computer Science and Mathematics Division at the Oak Ridge National Laboratory, which is managed by UT-Battelle, LLC under Contract No. DE-AC05-00OR22725. The authors thank B. Jolene Jones for assistance in manuscript preparation, and George Ostrouchov and Paul Wambach for comments on the material in this report and the related website. This work has been authored by a contractor of the U.S. Government. Accordingly, the U.S. Government retains a nonexclusive, royalty-free license to publish or reproduce the published form of this work, or to allow others to do so for U. S. Government purposes

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