Table AV
Comparison of Parameter Estimates For ERR Main Effects
Model1 All Cancer with Ten Year Lag (N=28,347)
White Males Ever Employed at X-10 or Y-12 Between 1943 and 1984
Internal2 External/Internal3
TERM Estimate SE Estimate SE
Age 5.20 0.22 -0.27 0.38
1900 0.538 0.132 -9.2 13.4
1900--09 0.731 0.102 -4.3 10.3
B - 1910--19 0.728 0.093 -10.1 9.3
1920--29 0.565 0.103 -25.0 10.3
1930+ 0.072 0.181 -66.2 17.8
S4- Nonmonthly 0 . 0 .
Monthly vs Nonmonthly -41.9 8.3 -41.3 8.3
L - Worked at Least 1 Year 0 . 0 .
Worked less than 1 Year 11.8 9.1 11.3 9.1
IG- Eligible Not Monitored 0 . 0 .
Eligible and Monitored 5.8 7.5 4.3 7.5
Not Eligible 2.6 8.7 2.9 8.7
F - X-10 Only 0 . 0 .
Y-12 Only vs X-10 Only 15.6 8.6 15.3 8.6
Multiple vs X-10 Only 6.1 7.8 5.9 7.8
D5- External Dose (Sv) 1.52 0.82 1.45 0.81
95% CI (0.18, 3.59 ) (0.15, 3.48)
- ERR main effects model: rate = exp[Age Term +B+S+L+IG+F] (1+D).
- For internal analysis baseline rates are estimated using log
(age/52.5) for the age term, so that for B=1910-19, exp(.743)=2.11
cancer deaths per 1000. Note that for U.S. white males born in 1915
the cancer mortality rate at age 52.5 is 2.24/1000.
- For External/Internal model baseline rates are estimated using
log (known rates from vital statistics for U.S. white males) as an
"offset" as part of the age term. Consequently, for B=1910-19,
exp(-8.5/100)=.907, is the estimated SMR for the 1915 birth cohort at
the reference level of the other terms. The age variable, defined as
(age-52.5)/100, was included to reflect any systematic age related
departures from the external rates.
- The coefficients for the factors S, L, IG, and F are relative
risk estimates in L% units, i.e. the cancer relative risk estimate for
monthly vs non-monthly workers is exp(-41.9/100)=0.66.
- ERR per Sv with 95% likelihood based confidence intervals.

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