Corrigenda to
RE: Toxicology Volume 183, Issues 1-3, 1 February 2003, Pages 39-56
Identification of an abnormal beryllium lymphocyte proliferation test
Thanks to Drs Stange and Furman, ORISE-Rocky Flats for identifying these errors
1) Throughout the paper all "logs" are base e, i.e. Ln(x) and log(x)
mean the same thing
/x
| 1
log(x) = | -- dt for x in <0, +infinity> = Ln(x) ,
/ 1 t
the "natural logarithm" as usually defined in mathematics. Unfortunately,
none of the authors, reviewers, or editors noticed this inconsistency.
In the pre-computer days ( say < 1960) when tables were used to find
"logs", base 10 was used as a matter of computation convenience.
The most flagrant inconsistency occurs in Step 5 of Sec 2.2, i.e.
SLsi = Ln(SI)/SE[log(SI)] should be SLsi = Ln(SI)/SE[Ln(SI)]
In some figures LN(M,S) is used to represent the log normal
distribution with location parameter M and scale parameter S.
2) On page 50 Change:
"... in Serum 3040083 is 48/56 or 85.7% 1- and the specificity (false
positive rate) is 992/1024 or 96.9%"
To:
"... in Serum 3040083 is 48/56 or 85.7% and the specificity (1 - false
positive rate) is 992/1024 or 96.9%"
3) Exhibit A4 Pages 54-55 should appear as
Toxicology Feb 2003, Pages 54-55 Exhibit A4
Additional corrections on Mar 30 2006
The result 0.230 and all other calculations are correct as far as I know.
Change 0.3183*sqrt(1.571 x 0.25) to 0.3183*sqrt(1.571 x (4/12) )